The Journal
Evidence, unfiltered.
Clinical research on metabolic health, hormones, peptides and longevity — read and translated by the physicians behind Kove RX.
Longevity · 3 min read
NAD+ and cellular energy: what the science supports
A review of the current evidence surrounding NAD+ levels, cellular metabolism, and the clinical reality of supplementation for longevity.
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Nutrition · 4 min read
How much protein you actually need during medical weight loss
A precise guide to protein intake for patients using GLP-1 medications to ensure weight loss comes from adipose tissue rather than skeletal muscle.
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Weight Loss · 3 min read
Why weight comes back after stopping a GLP-1 — and what to do
Understanding the metabolic shifts that occur when discontinuing GLP-1 therapy is essential for maintaining long-term weight health.
Read articleWeight Loss · 4 min read
Managing GLP-1 side effects: a practical, physician-led guide
An evidence-based guide to mitigating common GLP-1 side effects through clinical protocols and lifestyle adjustments.
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Weight Loss · 4 min read
Metformin beyond diabetes: what the longevity data really shows
Evidence suggests metformin may influence metabolic pathways related to aging and weight regulation beyond its primary role in blood sugar control.
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Weight Loss · 3 min read
Protecting muscle while losing fat on a GLP-1
A physician-led guide to mitigating lean mass loss during GLP-1 therapy through protein intake, resistance training, and clinical monitoring.
Read articleWeight Loss · 3 min read
Semaglutide explained: how GLP-1 therapy actually changes appetite
A detailed look at how semaglutide targets the brain and digestive system to regulate satiety and reduce food noise.
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Weight Loss · 4 min read
The benefits of tirzepatide, according to the science
Dual GIP and GLP-1 activation has produced some of the largest weight-loss results ever recorded in clinical trials — plus meaningful metabolic and cardiovascular gains.
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